Applied Biopharmaceutics Pharmacokinetics, 7e Shargel L, Yu AC.

Shargel L, Yu A.C.

Leon Shargel, and Andrew B.C.

New York, NY:. SAS 1 is regarded as the industry standard for clinical data analysis and reporting; however, Phoenix WinNonlin 2, which is a powerful tool tailored to the specific demands of PK data, is widely accepted as the industry standard for PK data analyses.

Figure 1: Aesthetic differences between SAS and Phoenix WinNonlin outputs SAS WinNonlin SAS WinNonlin Phoenix WinNonlins advanced reporting capabilities are very useful when compiling stand-alone PK reports, facilitating rapid illustration of PK data through workflows and templates; however, when results are integrated into a large CSR, it is often preferable to generate TLFs in SAS for consistency with the remainder of the clinical report (e.g.

Safety and efficacy data).

Phoenix Winnonlin Software Packages Such

Devising robust procedures using SAS transport files and CDISC nomenclature enables a readily switch between Phoenix WinNonlin and SAS (not to mention other software packages such as NONMEM 3) to produce TLFs in a format which is suitable for each individual studys reporting requirements.

Although the main aspect of any should be ensuring that the correct approach has been used (e.g.

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Ultrafiltration for the analysis of free platinum concentrations (using.

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